Pierrel Research USA Inc, Wayne, Pa, has launched Orabloc™ (Articaine hydrochloride 4% with epinephrine 1:100,000 and Articaine hydrochloride 4% with epinephrine 1:200,000). Orabloc is a new, purer formulation of Articaine with epinephrine, an injectable dental anesthetic for routine dental procedures and oral surgery.

According to the company, Orabloc requires less overage of epinephrine than previous formulations of Articaine, so there is less vasoconstrictor in each injection. This is consistent with recommendations from the American Heart Association to use the lowest available amount of vasoconstrictor.

Orabloc offers the same rapid onset of action that dentists expect from existing Articaine: anesthesia within 1 to 9 minutes, with complete anesthesia lasting about 1 hour for infiltrations and up to 2 hours for nerve block.

Orabloc will be available through Patterson Dental.

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